Spontaneous Precipitation of Brushite in Urine: Evidence that Brushite Is the Nidus of Renal Stones Originating as Calcium Phosphate
نویسندگان
چکیده
منابع مشابه
Dynamical model of brushite precipitation
The objectives of this work are twofold. From academic point of view the aim is to build a dynamical macro model to fit the material balance and explain the main kinetic mechanisms that govern the transformation of the hydroxyapatite (HAP) into brushite and the growth of brushite, based on laboratory experiments and collected database. From practical point of view, the aim is to design a reliab...
متن کاملEpitaxial relationships in urolithiasis: the brushite-whewellite system.
1. Whewellite (calcium oxalate monohydrate) crystals were found to induce epitaxially the heterogeneous nucleation of brushite (calcium monohydrogen phosphate dihydrate) from its metastable supersaturated solution in approximately one-quarter of the time required for spontaneous precipitation in the absence of added nucleating agents. Scanning electron-microscope observation of the crystalline ...
متن کاملPhysicochemical basis for formation of renal stones of calcium phosphate origin: calculation of the degree of saturation of urine with respect to brushite.
Brushite (CaHPO(4).2H(2)O) was considered to govern the formation of renal calculus of calcium phosphate origin. The degree of saturation of urine with respect to this phase was therefore calculated. This value was obtained from the ratio of the activity product of Ca(++) and HPO(4) (m) (K(sp)) before and after incubation of urine with brushite. The errors in the calculation of K(sp) were large...
متن کاملVisualising phase change in a brushite-based calcium phosphate ceramic
The resorption of brushite-based bone cements has been shown to be highly unpredictable, with strong dependence on a number of conditions. One of the major factors is phase transformation, with change to more stable phases such as hydroxyapatite affecting the rate of resorption. Despite its importance, the analysis of phase transformation has been largely undertaken using methods that only dete...
متن کاملDicalcium phosphate cements: brushite and monetite.
Dicalcium phosphate cements were developed two decades ago and ever since there has been a substantial growth in research into improving their properties in order to satisfy the requirements needed for several clinical applications. The present paper presents an overview of the rapidly expanding research field of the two main dicalcium phosphate bioceramics: brushite and monetite. This review b...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1971
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.68.7.1456